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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
BP-1-102/ 17o Influence on proliferation Proliferaion Assay 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on proliferation Proliferaion Assay 5.00 µM Burktte Mus musculus
BP-1-102/ 17o Influence on proliferation Proliferaion Assay 5.00 µM Jurkat T-ALL Mus musculus
BP-1-102/ 17o Influence on tumor growth Individual tumor size 3.00 mg/kg REH tumor Mus musculus
BP-1-102/ 17o Influence on tumor growth Mean tumor size 3.00 mg/kg REH tumor Mus musculus
BP-1-102/ 17o Influence on protein Western Blot 5.00 µM REH-B-ALL Mus musculus p-STAT3
BP-1-102/ 17o Influence on protein Western Blot 5.00 µM REH-B-ALL Mus musculus STAT3
BP-1-102/ 17o Influence on gene expression RT-qPCR 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 2.50 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 2.50 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 2.50 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on cell viability MTT Assay 5.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on cell viability MTT Assay 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on cell viability MTT Assay 5.00 µM UW288 Homo sapiens
BP-1-102/ 17o Influence on cell viability MTT Assay 10.00 µM UW288 Homo sapiens
BP-1-102/ 17o Influence on cell proliferation BrdU assay 5.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on cell proliferation BrdU assay 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on cell proliferation BrdU assay 20.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on cell proliferation BrdU assay 5.00 µM UW288 Homo sapiens
BP-1-102/ 17o Influence on cell proliferation BrdU assay 10.00 µM UW288 Homo sapiens
BP-1-102/ 17o Influence on cell proliferation BrdU assay 20.00 µM UW288 Homo sapiens
BP-1-102/ 17o Influence on protein Western Blot 10.00 µM DAOY Homo sapiens p-STAT3 (Y705)
BP-1-102/ 17o Influence on protein Western Blot 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on protein Western Blot 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on protein Western Blot 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on protein Western Blot 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on protein Western Blot 10.00 µM DAOY Homo sapiens STAT3
BP-1-102/ 17o Influence on protein Western Blot 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Influence on protein Western Blot 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Production of lactate Glycolisys assay 5.00 µM DAOY Homo sapiens
BP-1-102/ 17o Production of lactate Glycolisys assay 10.00 µM DAOY Homo sapiens
BP-1-102/ 17o Production of lactate Glycolisys assay 20.00 µM DAOY Homo sapiens
BP-1-102/ 17o Production of lactate Glycolisys assay 5.00 µM UW288 Homo sapiens
BP-1-102/ 17o Production of lactate Glycolisys assay 10.00 µM UW288 Homo sapiens
BP-1-102/ 17o Production of lactate Glycolisys assay 20.00 µM UW288 Homo sapiens
BP-1-102/ 17o Influence on STAT3 activation EMSA 5.00 µM Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 10.00 µM Homo sapiens STAT1:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 20.00 µM Homo sapiens STAT1:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 10.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 20.00 µM MDA-MB-231 Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 10.00 µM DU145 Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 20.00 µM DU145 Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 10.00 µM NIH3T3/ vSrc Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 20.00 µM NIH3T3/ vSrc Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 10.00 µM Panc-1 Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 20.00 µM Panc-1 Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 10.00 µM A549 Homo sapiens STAT3:STAT3
BP-1-102/ 17o Influence on STAT3 activation EMSA 20.00 µM A549 Homo sapiens STAT3:STAT3